Papovaviridae

Properties of Papovaviridae 294

Papillomaviruses 294

Polyomaviruses 302

Further Reading 304

The main interest in papovaviruses lies in the probability that they cause cancer in humans, as certain members certainly do in other animal species. It has long been known that viruses of the genus Papillomavirus cause skin warts. More recently, however, it has become clear that papillomaviruses are a frequent cause ol sexually transmitted disease and are strongly linked to carcinoma of the cervix, one of the commonest cancers of women. Certain members of the genus Polyomavirus, on the other hand, infect most people subclinically, persist for life, and are frequently reactivated by immunosuppression.

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