J Virus Induced Changes in Cells

Types of Virus-Cell Interactions 74

Cytopathic Effects of Virus Infections 76

Mechanisms of Cell Damage 80

Noncytocidal Infections 81

Interferons 82

Further Reading 86

The "typical" virus-cell interaction described in Chapter 3 was a productive infection of a permissive celt by a cytoadal (iytic) virus, that is, resulting in the production ot infectious virions and the death of the host cell. It is important to appieciate that some cytocidal virus-cell encounters are nonproductive (abortive) and that some productive infections arc noncytocidal (nonli/ttc) (Table 5-1)

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