Enteric Parvoviruses

A confusing variety of "small round viruses" have been visualized by electron microscopy in feces from normal and ill people. Among those resembling parvovirus, some were from people with gastroenteritis acquired in a common-source outbreak, such as consumption of raw shellfish. None of these "fecal" parvoviruses has been shown to bear any serological relationship to B19 (or AAV), although nucleotide sequencing of their DNA reveals striking homology with B19, particularly in the left side of the genome which encodes the nonstructural proteins. The relationship between the two and the clinical importance of fecal parvoviruses need to be established.

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