Three experimental systems have been particularly useful for measuring the activation and effector phases of cell-mediated cytotoxic responses. The mixed-lymphocyte reaction (MLR) is an in vitro system for assaying TH-cell proliferation in a cellmediated response; cell-mediated lympholysis (CML) is an in vitro assay of effector cytotoxic function; and the graft-versus-host reaction (GVH) in experimental animals provides an in vivo system for studying cell-mediated cytotoxicity.
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This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.