intravenous therapy using long term intravenous access catheters (i.e., Hickman catheters) decreases length of hospital stays (50-52). Oral therapy using the quinolone class of antibiotics for Gram-negative organisms is currently being used in adults with osteomyelitis (45). None of the current quinolones provides optimal antistaphylococcal coverage, an important disadvantage in view of the rising incidence of nosocomially acquired staphylococcal resistance (53). Further, the currently available quinolones provide essentially no coverage for anaerobic pathogens.

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How To Win Your War Against Bronchitis

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