intravenous therapy using long term intravenous access catheters (i.e., Hickman catheters) decreases length of hospital stays (50-52). Oral therapy using the quinolone class of antibiotics for Gram-negative organisms is currently being used in adults with osteomyelitis (45). None of the current quinolones provides optimal antistaphylococcal coverage, an important disadvantage in view of the rising incidence of nosocomially acquired staphylococcal resistance (53). Further, the currently available quinolones provide essentially no coverage for anaerobic pathogens.
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If you suffer with asthma, you will no doubt be familiar with the uncomfortable sensations as your bronchial tubes begin to narrow and your muscles around them start to tighten. A sticky mucus known as phlegm begins to produce and increase within your bronchial tubes and you begin to wheeze, cough and struggle to breathe.