Prescribing dings is one matter, taking them is another. About 50% of patients are non-compliant. However, many doctors assume compliance unless the contrary is obvious. Sometimes non-compliance can be established by absent plasma concentrations of drugs or suspected by the lack of common adverse effects such as a dry mouth with tricyclic antidepressants. Inquiring about compliance requires tact
Normal male Normal female Mating
Parents with son and daughter (in order of birth)
Female with children by two males
Number of children of sex indicated
Affected male Affected female Propositus
Heterozygotes for autosomal genes
Carrier X-linked recessive gene
Abortion or stillbirth of unspecified sex
Identification of person in pedigree from the generation (Roman numerals) and the location in I the generation. Proposita is lll4
Fig. 1.7 Symbols used in pedigree charts. Drawing up a family tree begins with the affected person first found to have the Irait (propositus if male, proposita if female). Thereafter, relevant information regarding siblings and all material and palernal relatives is included. (Reproduced with permission from Emery A E H, Mueller R F 1992 Elements of medical genetics, 8th edn. Churchill Livingstone. Edinburgh.)
and rapport. Poor compliance may not be wilful and many patients may be unaware of the extent of their noncompliance and embarrassed when questioned.
Was this article helpful?