Outcome Measures

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Diaries were kept throughout the study period, recording sexual acts (intercourse masturbation), occurrence of ejaculation, and subjective quality of the sexual act (1 = unpleasant to 4 = very satisfactory). The men also made weekly ratings of frequency of sexual thoughts and the extent to which those thoughts were associated with sexual excitement and mood (Lorr and McNair Mood Check List), giving scales for anxiety/tension, depression, anger, vigor and fatigue.

At monthly interviews, the investigator rated the patient's enjoyment of sexual contact and his erectile and ejaculatory difficulties. Blood was also collected monthly for endocrine assessment (testosterone, 5 a-dihydrotestosterone, estradiol, sex hormone-binding globulin [SHBG], FSH, LH, and prolactin).

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