To address the clinical issues and problems that need resolution and recommendations (see Subheading 2.), there must be support for research. The major support for aging research comes from the National Institute on Aging, the Department of Veterans Affairs, foundations, and industry. However, funding for investigations on issues related to infectious diseases and aging is relatively limited. Support for these types of research should also be sought from other agencies within the National Institutes of Health, i.e., National Institute for Allergy and Infectious Diseases, National Heart, Lung, and Blood Institute, and National Cancer Institute, because of the cross-cutting nature of diseases affecting the elderly and their secondary complication of infection.
Professional societies hosting meetings for presentation of research findings should reserve a section for aging research in their program. Organizations such as the Infectious Diseases Society of America, Interscience Congress on Antimicrobial Agents and Chemotherapy (American Society for Microbiology), and Society for Healthcare Epidemiology of America should consider having a special category of "aging" for abstract presentation. Finally, journals that publish research findings on infectious diseases-related topics should feature a section on investigations in the area of aging (geriatrics and gerontology) and long-term care.
1. McGinnis, J. M. (1988) The Tithonous syndrome: health and aging in American, in Health Promotion and Disease Prevention in the Elderly (Chernoff, R. and Lipschitz, D. A., eds.), Raven Press, New York, pp. 1-15.
2. Yoshikawa, T. T. (1994) Infectious diseases, immunity and aging. Perspectives and prospects, in Aging, Immunity and Infection (Powers, D. C., Morely, J. E., and Coe, R. M., eds)., Springer Publishing, New York, pp. 1-11.
3. Yoshikawa, T. T. (1997) Perspective: aging and infectious diseases: past, present and future. J. Infect. Dis. 176, 1053-1057.
4. High, K. and Yoshikawa, T. T. (1999) Introduction: integrating geriatrics into the subspecialty of infectious diseases. Clin. Infect. Dis. 28, 708-709.
5. Gleckman, R. A., Bradley, P. J., Roth, R. M. et al. (1985) Bacteremic urosepsis: a phenomenon unique to elderly women. J. Urol. 133, 174,175.
6. Yoshikawa, T. T., Nicolle, L. E., and Norman, D. C. (1996) Management of complicated urinary tract infection in older patients. J. Am. Geriatr. Soc. 44, 1235-1241.
7. Nicolle, L. E., Duckworth, H., Brunka, J., et al. (1998) Urinary antibody level and survival in bacteriuric institutionalized older subjects. J. Am. Geriatr. Soc. 46, 947-953.
8. Woodhead, M. (1994) Pneumonia in the elderly. J. Antimicrob. Chemother. 34(Suppl. A), 85-92.
9. Fine, M. J., Stone, R. A., Singer, D. E., et al. (1999) Processes and outcomes of care for patients with community-acquired pneumonia. Arch. Intern. Med. 159, 970-980.
10. Riquelme, R., Torres, A., El-Ebiary, M., et al. (1996) Community-acquired pneumonia in the elderly: a multivariate analysis of risk and prognostic factors. Am. J. Respir. Crit. Care Med. 154, 1450-1455.
11. Marrie, T. J. (1999) Clinical strategies for managing pneumonia in the elderly. Clin. Geriatr. (Suppl.) August, pp. 6-10.
12. Rajagopalan, S. and Yoshikawa, T. T. (1999) Tuberculosis, in Principles of Geriatric Medicine and Gerontology, 4th ed. (Hazzard, W. R., Blass, J. P., Ettinger, W. H., Jr. et al., eds.) McGraw-Hill, New York, pp. 737-744.
13. Battershill, J. H. (1980) Cutaneous testing in the elderly patient with tuberculosis. Chest 77, 188,189.
14. Weinsein, P., Murphy, J. R., Reller, L. B., et al. (1988) The clinical significance of positive blood cultures: a comprehensive analysis of 500 episodes of bacteremia and fungemia in adults. II. Clinical observations, with special reference to factors influencing prognosis. Rev. Infect. Dis. 5(1), 54-70.
15. Weil, M. H., Shubin, H., and Biddle, M. (1964) Shock caused by gram-negative microorganisms. Analysis of 169 cases. Ann. Intern. Med. 60(3), 384-400.
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