Inulintype Fructans And Lipid Homeostasis

11.3.1 Animal Data

The hypothesis that inulin-type fructans might modulate the metabolism of lipids originates in an experiment protocol to evaluate their caloric value (see Chapter 7). Indeed, at the end of the treatment period, analysis of total body composition of oligofructose-fed rats (20% w/w in diet for 6 weeks) revealed a reduction in total body fat mass as compared to age-paired rats fed a control diet (Roberfroid unpublished results).

These data have since been confirmed in a variety of models (Table 11.1) designed to study the effects of inulin-type fructans on blood and/or liver lipid parameters.

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