Corticosteroids have no benefit as a maintenance therapy . Over the past 10 years, a newer steroid, budesonide, which showed several features that made it particularly suitable for study as a long-term anti-inflammatory agent in Crohn's disease, has generated interest. It has a high first-pass hepatic metabolism and high steroid receptor affinity. Controlled release preparations were developed that delivered high ileal concentrations of the drug taken orally to produce considerable topical anti-inflammatory activity with a decreased systemic effect .
The theoretical benefits of budesonide seem to be at a dose of 6 mg or greater for those who underwent resection for active ileocecal disease rather than fibro-stenotic disease. Despite this, a recent RCT has shown no benefit of therapy. In summary, corticos-
teroid use is not indicated for postoperative patients to prevent recurrence.
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Everything you wanted to know about. How To Cure Tennis Elbow. Are you an athlete who suffers from tennis elbow? Contrary to popular opinion, most people who suffer from tennis elbow do not even play tennis. They get this condition, which is a torn tendon in the elbow, from the strain of using the same motions with the arm, repeatedly. If you have tennis elbow, you understand how the pain can disrupt your day.