Longterm Complications

Desmoid tumours are known to occur in 5-15% of patients with FAP and known to cluster in families [32]. The conversion of IRA to IPAA may not be possible due to the presence of low rectal cancer or an abdominal desmoid tumour [24]. The question of whether an IPAA or IRA affects the development of intra-abdominal desmoid tumour is also unclear [33, 34], with some suggesting that this may be greater in IPAA due to increased handling and mobilisation of the small bowel mesentery [14]. Other long-term adverse events include perianal irritation and anastomotic stricture formation [35].

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