The need to formulate a correct diagnosis of ulcerative colitis (UC), based also on histopathological findings, for differential diagnosis from Crohn's disease (CD) and to establish site and extension of the disease are indications for colonoscopy in UC patients. In patients with certain diagnosis, colonoscopy is the gold standard to identify preneo-plastic lesions (dysplasia) during surveillance for col-orectal cancer (CRC), which is more common in patients with UC than in the general population (Table 1).

Table 1. Colonoscopy role in management of ulcerative colitis (UC)

Diagnostic validation Extension of UC

Conventional medical therapy failure Complication onset (stenosis, dysplasia, cancer)

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