Surgical treatment for UC patients is usually indicated due to one of three causes: (1) failure of medical therapy or dependence on therapy, mainly corticos-teroids, with severe side effects; (2) prevention when dysplasia is diagnosed and treatment of colorectal cancer (CRC); and (3) a severe acute complication of UC, such as toxic megacolon or massive hemorrhage. The appropriate timing of elective surgery is determined by collaborative assessment of the gastroenterologist and the surgeon and should be tailored to each patient according to the specific clinical setup.
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