Early Post Operative Morbidity

Early post-operative complications such as bowel obstruction, haemorrhage, intra-abdominal sepsis, anastomotic separation, wound infection, and the need for 30-day re-operation were reported by the ten studies shown in Table 2. The results from meta-analysis of post-operative complications from these studies are shown in the Forrest plot in Fig. 1. Please note that squares indicate point estimates of treatment effect (odds ratio), with the size of the square representing the weight attributed to each study and 95% confidence intervals indicated by horizontal bars. The diamond represents the summary odds ratio from the pooled studies with 95% confidence intervals. There was no significant difference between IRA and IPAA groups in the incidence of bowel obstruction, post-operative haemorrhage, intra-abdominal sepsis, anastomotic separation, and post-operative wound infection. There was however a significantly reduced need for re-operation within 30 days of 11.6% with IRA vs. 23.4% with IPAA (OR 2.11, CI 1.21-3.70).

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