Discrete Adenomas and Carcinomas of the Colon

Whereas polyposis syndromes are rare, discrete adenomas in small numbers occur in from 10% to 50% of the general population. Overall, colorectal cancer may affect 3% of the population. The inheritance pattern of these cases is largely unknown. Park et al. [11] studied a large groups with clusters of colorectal cancer. Extensive screening with flexible proctosigmoi-doscopy revealed adenomas in 21% of the 191 pedigree members in contrast to 9% of controls. The excess of adenomas showed autosomal dominant inheritance. A subsequent expanded study of 670 persons in 34 kindreds revealed the estimated prevalence of adenoma at age 60 years in related family members was 24% whereas that in unrelated spouses was 12%. Such studies emphasise the importance of screening for colorectal tumours in first-degree relatives of patients with these lesions.

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Confident Kids

Confident Kids

Although nobody gets a parenting manual or bible in the delivery room, it is our duty as parents to try to make our kids as well rounded, happy and confident as possible. It is a lot easier to bring up great kids than it is to try and fix problems caused by bad parenting, when our kids have become adults. Our children are all individuals - they are not our property but people in their own right.

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