Dietary Restriction Social and Sexual Dysfunction

Eat Stop Eat

Best Weight Loss Programs That Work

Get Instant Access

The studies reporting on dietary restriction, social restriction, and sexual dysfunction are shown in Table 4. The results from meta-analysis of these outcomes are shown in the Forrest plot in Figs. 3 and 4. The incidence of social restrictions following 58 IPAA and 85 IRA procedures (33, 35), was found to be significantly lower at 3.5% following IRA as compared to 13.8% following IPAA (OR=6.04, CI 1.53-23.78). There was no significant difference between IPAA and IRA in terms of need for dietary restriction and male and female sexual dysfunction.

Table 2. Studies reporting early post-operative complications

Author Early post-operative complications

Table 2. Studies reporting early post-operative complications

Author Early post-operative complications

Bowel

Haemorrhage

Abdominal

Anastomotic

Wound

30-day

obstruction

sepsis

separation

infection

reoperation

Ambrose [2]

*

*

Bjork [31]

*

*

*

*

*

*

Gunther [37]

*

*

*

*

*

Madden [35]

*

*

*

*

*

*

Penna [29]

*

*

Rodriguez [42]

*

*

*

*

Soravia [20, 24]

*

*

*

*

*

Tonelli [14]

*

*

*

Van Duijvendijk [44]

*

*

*

Ziv [13]

*

*

Fig. 1. Meta-analysis of post-operative complications

Table 3. Studies reporting long-term complications

Author Long-term complications

Perianal Anastomotic Intra-abdominal Cancer in Reoperation irritation stricture desmoids pouch/rectum on rectum

Ambrose [2] Bjork [31] Ko [41] Madden [35] Penna [29] Rodriguez [42] Soravia [20, 24] Tonelli [14] Van Duijvendijk [44] Ziv [13]

Review: PA vesus ff>AA for FAP (Version 03)

Comparison: 03 Post-operative otJcomes Outcome: 02 Long-term adverse events

Study or siA.category

IPAA

rrfj

Oft (random)

Oft (random)

01 Peri-anal inflation

Madden 17/20

Ambrose 30/91

Toneii 0/24

Soravia 29/48

van OuijvsntifS; 102/118

Ko 10/30

BjOfk 14/20

Subtotal (95% O) 346

Test lor heterogeneity: OW - 9 63. dl = 5 (P . O.OSt), l> - 48.1% Test for 0V«rM ellect: Z - 2.95 (P - 0.003)

02 Aftflstorrfltic stricture

Mstwen 1/23

Ziv 1/7

Soravia 2/50

Van Duiivendi* 12/1 IB Bjork 0/20

Subtotal (9S% CD 213

Test lor heterogeneity: Cn' -1.99. dl - 3 (P - 0.58), I" - 0%

03 Hra-adbotiwwt desmoids Ambrose

Tones Soravia Van Duijvend^i Subtotal (9S% CI) Tolet events: 11 (IPAA). 34 (IRA)

Test lor heterogeneity: On1 = 2.31, dl • 5 (P - 0.80) I" - 0% Testier overal elfect: 34 (f>»0.18)

04 Cancer m D0«h I reta*>etf rectun Airijrose 0/91 Rodriguez 0/11 Soravia 0/38

Van Dtiyvend* 0/118

BjKt 0/20

SuDtotal (95% CI) 278

Test lor heterogeneity: Cin' - 0.53, df- 3(P ■ Oil}, I" - 0%

05 Need for salvage surgery ! failure Ambrose 1/91 Ro<*$uez 0/11 Tonelfr 0/24 Soravia 3/50 Van Duijvendjc 4/118 Bjork 1/20 SuMrtsI (95% CI) 314 Torn events: 9 (PAA), 80 (IRA)

Test tor heterogeneity: CW = 5 20, dl ■ 1 (P - 027), I" - 23.1% Test tor Overei effect: Z >5.19 (P e 0.00001)

0/13

16.07 17.59

18.19 19.26 11.83 17.00 100.00

16.59

27.70 35.53

100.00

16.62 12.68

25.54 27.19 17.97 100.00

2.77 10.17, 46.261 8,03 (0,23, 224,43) 1.21 10.16, 8.90) 5.98 11.64. 21.631

0.61 10.02, 15.651 1.38 10.26, 6.881 0.23 10.01, 8.081 0.66 (0.14. 3.011 0,32 (0,03, 1.23) 0,81 10.29, 2.29) 0.88 (0.34, 1.22)

0.05 10.00, 1.31) 0.13 (0.01, 2.44) 0.18 to.01, 2.77) 0.23 10.01, S.731 0.13 10.03, 0.611

0,03 (0,01, 0.12) 0,14 (0-05, 0.41) 0.51 (0.05, 4.91) 0.10 (0.04, 0.231

1991

1992 1997 1999

1999

2000 2001

1991 1995 1999 1999 2001

1992

1993 199 S 1997 1999 1999

1992 1992 1999 1999 2001

1992 1992 1997 1999 1999 2001

0.001 0.01 0.1 1 10 100 1000 Favours PAA Favours IRA

Fig. 2. Meta-analysis of long-term complications

Table 4. Studies reporting dietary restriction, social restriction and sexual dysfunction

Author

Quality of life

Dietary restrictions

Social restrictions

Male sexual dysfunction

Female sexual dysfunction

Ambrose [2] Bjork [31] Gunther [37] Ko [41] Madden [35] Penna [29] Rodriguez [42] Rotondano [43] Soravia [20, 24] Tonelli [14] Van Duijvendijk [44]

Review: RA vesus PAA for FAP (Version 03)

Comparison: 02 Quality of life

Outcome: 01 Dietary and social restrictions

Study or iutkcategwy

IPAA

IRA n/N

Oft (random)

01 Dietary reselrictiûns

MaciiJen 11/20 29/60

Perma 98/120 23/23

Soravia Z2/43 17/40

Vsn DuijvenW 69/118 111/161

Etorn 19/47 4/29

Suttotal (95% Ci) 378 327 Total events: 212 (IPAA), 190 (IRA)

Test 1er heteroaeneity: On'- 17.î3.dt ■ S(P ■ 0.004),I* ■ 71.0* Test lor ovMenect: Z- 033 (P ■ 041)

02 Social restrictions

Matfden s/zo 3/60

SuWofal (95% Cl) se Si Total events 8 (PAA), 3 (FAI

Test tor heternçenerty: On1 - 0.02, dl « 1 (P ■ 0.B9),P-0* Test lor overei etfsct: 1 ■ 2.S7 (P ■ 0.01)

18.

51

1.

31

10.47,

3.61]

6.

.52

O.

09

to.Ol.

1.591

19.

99

1.

42

to.60,

3.37)

23.

31

0.

63

10.39,

1.04}

IS.

02

5.

33

11. 33,

21,33]

IS.

65

3.

88

11,16,

12.S9]

100.

00

1.

40

10.63,

3.10)

0.001 0.01 0.1 1 10 100 1000 Favours PAA Favours IRA

6.33 II.36r 29.55Ï £.03 (0.25,. 101.66] 6.04 11.53. 23.781

1991 1993 1999

1999

2000 2001

1991 2001

Fig. 3. Meta-analysis of dietary and social restrictions

Was this article helpful?

0 0
4 Steps To Permanent Weight Loss

4 Steps To Permanent Weight Loss

I can't believe I'm actually writing the book that is going to help you achieve the level of health and fitness that you always dreamed of. Me, little scrawny sickly Darlene that was always last picked in gym class. There's power in a good story here so get this book now.

Get My Free Ebook


Post a comment