This is often not a simple issue. The classical clinical pattern is well known, but the symptoms are not so clear and the differential diagnosis includes infective diarrhoeas, drugs intolerance, haematological diseases and neoplasia. Once the diagnosis of IBD is clear, we have to remember, before starting with therapy, that 50% of relapses are associated with pathogens. Moreover, the radiologist, the endo-scopist and the pathologist should have detailed information about the clinical situation, so that they can make every effort to get the right diagnosis. That means that special attention and training in this dis ease is required for any specialist involved in the diagnostic process.
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