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Part 1: BASIC FOUNDATIONS OF CARDIOLOGY Chapter 6:
MOLECULAR AND CELLULAR BIOLOGY OF BLOOD VESSELS Authors: Kathy K. Griendling, David G. Harrison, R. Wayne Alexander
It has become apparent that a diverse number of pathologic processes all contribute to common vascular diseases such as atherosclerosis and hypertension. During the past several years, these pathologic events have been defined with increasing clarity at a cellular and molecular level, and strategies are emerging to treat these primary processes rather than simply treating the secondary manifestations of vascular disease. Because of this, understanding normal function of vascular cells and how these are altered by various vascular insults has become essential for both basic investigators and clinicians caring for patients with peripheral vascular disease, coronary artery disease, and hypertension. This chapter is designed to introduce important concepts in vascular biology and to emphasize how fundamental aspects of vascular control are altered by common disease conditions.
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Your heart pumps blood throughout your body using a network of tubing called arteries and capillaries which return the blood back to your heart via your veins. Blood pressure is the force of the blood pushing against the walls of your arteries as your heart beats.Learn more...