Fibric Acid Derivatives

Fibric acid derivatives, the third group of antihyperlipi-demic drugs, work in a variety of ways. Clofibrate (Atromid-S), acts to stimulate the liver to increase breakdown of very-low-density lipoproteins (VLDL) to low-density lipoproteins (LDL), decreasing liver synthesis of

VLDL and inhibiting cholesterol formation. Fenofibrate (Tricor) acts by reducing VLDL and stimulating the catabolism of triglyceride-rich lipoproteins, resulting in a decrease in plasma triglyceride and cholesterol. Gemfibrozil (Lopid) increases the excretion of cholesterol in the feces and reduces the production of triglycerides by the liver, thus lowering serum lipid levels.

Was this article helpful?

0 0
Lower Your Cholesterol In Just 33 Days

Lower Your Cholesterol In Just 33 Days

Discover secrets, myths, truths, lies and strategies for dealing effectively with cholesterol, now and forever! Uncover techniques, remedies and alternative for lowering your cholesterol quickly and significantly in just ONE MONTH! Find insights into the screenings, meanings and numbers involved in lowering cholesterol and the implications, consideration it has for your lifestyle and future!

Get My Free Ebook


Responses

  • Zoe
    Does fibric acid derivatives stimulate the liver to increase breakdown of vldl?
    8 years ago

Post a comment