During initial therapy, the most common adverse reactions seen are signs of overdose and hyperthyroidism (see Table 51-1). Adverse reactions other than symptoms of hyperthyroidism are rare.
These drugs are contraindicated in patients with known hypersensitivity to the drug or to any constituents of the drug, after a recent myocardial infarction (heart attack), or in patients with thyrotoxicosis. When hypothy-roidism is a cause or contributing factor to a myocardial infarction or heart disease, the physician may prescribe small doses of thyroid hormone.
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