Rhabdoid Tumor Of The Kidney

1. Occurs in 2% of renal tumors.

2. Chromosomal deletion of 22q11-12 is present in these patients.

3. More than 50% of patients are less than 1 year of age at diagnosis.

4. Metastases found in lung, liver, and brain.

5. Poor prognosis; mortality is over 80%. Responds poorly to current chemotherapy and radiotherapy. No satisfactory treatment available but intensive chemotherapy (ICE therapy; see page 556) followed by sublethal chemotherapy and peripheral stem cell rescue has been utilized with some success in our clinic.

Was this article helpful?

0 0

Post a comment