Pathology

Supratentorial lesions:

1. Cerebral hemisphere: low- and high-grade glioma, ependymoma, meningioma, primitive neuroectodermal tumor (PNET)

2. Sella or chiasm: craniopharyngioma, pituitary adenoma, optic nerve glioma

3. Pineal region: pineoblastoma, pineocytoma, germ cell tumors, glioma.

Infratentorial lesions:

1. Posterior fossa: medulloblastoma, glioma (low grade more frequent than high grade), ependymoma, meningioma

2. Brain stem tumors: low- and high-grade glioma, PNET

Table 17-1. Relative Frequency of Common Childhood Brain Tumors

Location and histology

Supratentorial

Low-grade glioma Ependymoma High-grade glioma PNET" Other Sella/chiasm

Craniopharyngioma Optic nerve glioma Total Infratentorial Cerebellum

Medulloblastoma Astrocytoma Ependymoma Brain stem Glioma Other Total

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