P

A, M

aP indicates preferred treatment in most cases (parentheses indicate drug is considered preferred treatment by some experts); A, efficacy less well established or alternative drug; M, for mild and moderately severe cases; S, combination recommended if infection is severe or central nervous system is involved. •"Efficacy and safety have not been established for children. "Usually in combination with itraconazole or a sulfonamide.

From Pickering LK, editor. Red Book: 2003 Report of the Committee on Infectious Diseases. 26th ed. Elk Grove Village, IL: American Academy of Pediatrics, 2003;725, with permission.

Table 26-7. Antifungal Agents and Doses

Drug

Route

Dose

Amphotericin B (Fungizone)

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