Intermediate Risk Bl Bll and DLCL

Patient eligibility criteria:

• Incompletely resected stage I

• All other stage II (except completely resected abdominal stage II)

• Stage IV (CNS negative, bone marrow with less than 25% blasts).

Treatment

See Table 16-7.

Results

A 90% 3-year EFS rate for all stages.

• Stage III, LDH less than twice normal: 92% 3-year EFS

• Stage III, LDH greater than twice normal: 86% 3-year EFS

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