Info

No change

>1.0

20% decrease

>1.5

30% decrease

>2.0

Hold for 24 hours

"Repeat anti-factor X level 4 hours post next dose until 0.5-1.0 units/mL, then once weekly at 4 hours post dose.

"Repeat anti-factor X level 4 hours post next dose until 0.5-1.0 units/mL, then once weekly at 4 hours post dose.

Antidote for Low-Molecular-Weight Heparin

• Termination of LMWH is usually sufficient.

• When an immediate effect is required, 1 mg protamine per 100 units (1 mg) of LMWH may be given.

• The protamine should be administered intravenously over a 10-minute period. A rapid infusion of protamine may cause hypotension.

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