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Abbreviations: FH, favorable histology; UH, unfavorable histology; DA, diffuse anaplasia; FA, focal anaplasia; AMD, dactinomycin (actinomycin D); VCR, vincristine sulfate; ADR, doxorubicin (Adriamycin).

Note: Babies <12 months of age should receive one-half the recommended dose of all drugs. Full doses lead to prohibitive hematologic toxicity in this age group. Full doses of chemotherapeutic agents should be administered to children >12 months of age.

aSee page 556 for precise protocol for ICE treatment. Although this protocol is not universally recommended, it has been used successfully by the author followed by stem cell transplantation in diffuse anaplasia.

Abbreviations: FH, favorable histology; UH, unfavorable histology; DA, diffuse anaplasia; FA, focal anaplasia; AMD, dactinomycin (actinomycin D); VCR, vincristine sulfate; ADR, doxorubicin (Adriamycin).

Note: Babies <12 months of age should receive one-half the recommended dose of all drugs. Full doses lead to prohibitive hematologic toxicity in this age group. Full doses of chemotherapeutic agents should be administered to children >12 months of age.

aSee page 556 for precise protocol for ICE treatment. Although this protocol is not universally recommended, it has been used successfully by the author followed by stem cell transplantation in diffuse anaplasia.

3. Radical excision is advised so that all tumor tissue can be completely removed. The junction of suspicious abnormal areas with normal kidney should be removed to facilitate the accurate diagnosis of small lesions.

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