Info

Scores for risk groups are as follows: low, 0; intermediate 1, 0.5-1.0; intermediate 2, 1.5-2.0; and high, >2.5. "Good, normal, -Y, del (5q), del (20q); poor, complex (>3 abnormalities) or chromosome 7 anomalies; intermediate, other abnormalities.

From Greenberg P, Cox C, LeBeau MM, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 1997;89:2074-88, with permission.

Scores for risk groups are as follows: low, 0; intermediate 1, 0.5-1.0; intermediate 2, 1.5-2.0; and high, >2.5. "Good, normal, -Y, del (5q), del (20q); poor, complex (>3 abnormalities) or chromosome 7 anomalies; intermediate, other abnormalities.

From Greenberg P, Cox C, LeBeau MM, et al. International scoring system for evaluating prognosis in myelodysplastic syndromes. Blood 1997;89:2074-88, with permission.

Table 13-16. FPC Scoring System for Prognostic Classification of Childhood MDSa

Criteria (before treatment) Points

Platelet count <40,000/mm3 1

Cytogenetic studies No detectable clonal abnormalities 0

Simple abnormalities arising from one event, i.e., single 1

translocation, other structural abnormalities, or gain or loss of one chromosome Complex abnormalities arising from two or more structural 2

or numerical events

Conclusion

Score 5-Year survival

aPatients included: MDS as per FAB classification, juvenile chronic myeloid leukemia, infantile monosomy 7 syndrome, MDS with eosinophilia.

Data tabulated from information available from Passmore SJ, et al. article Blood 1995;85:1742-50.

Table 13-17. International Prognostic Scoring System (IPSS)a for

Childhood MDS and JMML (European Working Group on MDS in Childhood)

Table 13-17. International Prognostic Scoring System (IPSS)a for

Childhood MDS and JMML (European Working Group on MDS in Childhood)

IPSS risk group

5-Year survival (%)

Low

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