Idiopathic pulmonary hemosiderosis, 75, 76 Imerslund-Grasbeck syndrome, 48t, 50, 51t, 52, 56t

Immune system late effects of childhood cancer, 770 tissue effects of iron-deficiency anemia, 37t Immune-tolerance induction (ITI), 319-320, 320t Immunodeficiencies associated with development of LPDs, 376-377 Immunoneutropenia, 223-225 Inappropriate antidiuretic hormone secretion syndrome, in tumor lysis syndrome, 699-700 Infantile pyknocytosis, 6t, 16 Infarct, arterial, antithrombotic therapy, 361 Infections bacterial, management of, 707t, 709-710t, 711 fungal, management of, 711, 714t, 715t, 717 hematologic manifestations, 78 in oncology patients, management of, 704-717 susceptibility of oncology patients to infections, 704 protozoan, 713, 715 viral, management of, 711, 716, 716t Infectious lymphocytosis, 84 Infectious mononucleosis chronic, 247-248 complications, 247t differential diagnosis, 242, 244 EBV-specific antibody responses, 246/ frequency of signs and symptoms, 244-245t laboratory findings, 245-246t treatment, 245 a-Interferon, treatment, congenital dyserythropoietic anemia, 103-104 Interleukin-ll, 726

Interleukin-2R, soluble (SIL-2R), reference values, 7991

Intestinal absorption, impaired, cause of iron-

deficiency anemia, 34, 35t Intranatal blood loss, 15

Intraplacental and retroplacental blood loss, 12 Intrauterine intravascular transfusion (IUIVT), 23 Intrinsic factor, deficiency (S-binder), 50, 56t Iron content of infant foods, 331 iron-containing compounds, 36t oral iron medications, 44 serum iron, total iron-binding capacity, and transfer-rin saturation during first year of life, 7811

iron and iron saturation percentage, 7811 iron and transferrin saturation values, 780/ Iron deficiency gastrointestinal tract, 72-73 infants at high risk for, 33t tissue effects of, 36-38t Iron (III) hydroxide sucrose complex, for iron-

deficiency anemia, 44-45 Iron-deficiency anemia causes, 321 classification, 35t cow's milk and, 34, 35t diagnosis blood findings, 38-40, 39t, 41t FEP levels, 38, 39t serum ferritin, 38-39, 40/ serum iron, 39 therapeutic trial, 39 differential diagnosis hypochromic anemia, 40-41, 411 microcytic anemia, 41, 43f, 43t etiologic factors blood loss, 321, 34 dietary requirements, 31 food iron content, 32-33, 33t growth, 33

impaired absorption, 34, 35t nonhematologic manifestations, 34, 36-38t exudative enteropathy in, 32t, 35t infants at high risk for, 33t iron-containing compounds, 36t prevalence, 31 prevention, 31

tissue effects of iron deficiency, 36-38t treatment blood transfusion, 45 nutritional counseling, 42, 44 oral iron medication, 44 parenteral therapy intramuscular, 44-45

intravenous, 45 partial exchange transfusion, 45-46 Iron-dextran, for iron-deficiency anemia, 44-45 Isovaleric acidemia, thrombocytopenia, 280 ITP. See Thrombocytopenic purpura: immune, idiopathic

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