Differential Diagnosis

This condition must be differentiated from:

• Transient erythroblastopenia of childhood: Table 6-3 differentiates TEC from DBA. Congenital hypoplastic anemia due to transplacental infection with B19

Table 6-3. Differentiating Transient Erythroblastopenia from Diamond-Blackfan Anemia

Feature

Transient erythroblastopenia

DBA (pure red cell aplasia)

Frequency

Common (? increasing)

Rare (5-10 per 106 live births)

Age at diagnosis

6 months-4 years,

90%, by 1 year

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