Diagnostic Evaluation

The following evaluations should be carried out:

1. History

2. Physical examination

3. Complete blood count (CBC)

4. Liver function tests, electrolytes, blood urea nitrogen (BUN), creatinine

5. a-Fetoprotein (AFP)

6. Human chorionic gonadotropin (0-hCG)

Table 24-1. Pathology of Germ Cell Tumors and Associated Markers

Histologic variant

Morphology

Common sites of origin

Markers*

Germinoma

Mature teratoma

6 Immature teratoma

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