Complications

Intravas'ular hemolysis:

Hemoglobinuria (dark urine) Iron deficiency Acute renal failure.

Venous thrombosis:

Peripheral veins

Superior and inferior vena cava

Hepatic veins (Budd-Chiari syndrome)

Mesenteric veins

Sagittal sinus

Splenic vein

Abdominal wall veins

Intrathoracic veins.

Defe'tive hematopoiesis:

Pancytopenia Macrocytosis Aplastic anemia Evolution to AML.

Infe'tious:

Sinopulmonary Blood borne.

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