Clinical Features

Patients commonly present with the following symptoms:

4. Pathologic fracture (16%).

It is important to realize that, because fever is a frequent symptom of Ewing sarcoma, it may be initially mistaken for osteomyelitis. The previous symptoms may be present for long periods of time, and more than 5% of patients have had symptoms for over 6 months before the tumor is identified. The pain may be intermittent.

Ewing sarcoma most commonly involves the lower extremity, with the pelvis being the next most common site. Table 21-6 lists the primary sites of origin in Ewing sarcoma. In long bones, Ewing sarcoma usually begins in the diaphysis.

Askin tumor is a PPNET of the thoracopulmonary region that involves the chest wall. It is seen more commonly in adolescent women. It is thought to arise from pluripotent cells along the intercostal nerves.

Was this article helpful?

0 0

Post a comment