Cavp

Lomustine (CCNU) 90 mg/m2 PO, day 1 Melphalan 7.5 mg/m2 PO, days 1-5 Etoposide 100 mg/m2 PO, days 6-10 Prednisone 40 mg/m2 PO, days 1-10, every 6 weeks EVAP

Etoposide 120 mg/m2 IV, days 1, 8, 15 Vinblastine 4 mg/m2 IV, days 1, 8, 15 Cytarabine 30 mg/m2 IV, days 1, 8, 15 Cisplatin 40 mg/m2 IV, days 1, 8, 15, every 4 weeks EPOCH

Etoposide 200 mg/m2 CIV, days 1-4 Vincristine 1.6 mg/m2 CIV, days 1-4 Doxorubicin 40 mg/m2 CIV, days 1-4 Cyclophosphamide 750 mg/m2 IV, day 6 Prednisone 60 mg/m2 PO, days 1-6 APE

Cytarabine (Ara-C) 375 mg/m2 IV bolus, followed by 375 mg/m2 infusion over 3 hours

Abbreviation: CIV, continuous intravenous infusion.

Cisplatin 15 mg/m2 IV infusion; starts 1 hour after cytarabine and continues for 2 hours Etoposide 20 mg/m2 IV at end of cytarabine, cisplatin infusion Repeat APE every 12 hours for 3-4 doses Cycle repeats every 3-6 weeks CEM

Lomustine (CCNU) 100 mg/m2 PO, day 1 Etoposide 100 mg/m2 PO, days 1-3, 21-23 Methotrexate 30 mg/m2 PO, days 1-8, 21, 28, every 6 weeks

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