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Babesiosis, hematologic manifestations, 84 Barth syndrome, 223

Bartonellosis, hematologic manifestations, 84 Basophilia, causes, 211t

Basophilic stippling, abnormalities in anemia, 7t, 153

Beckwith-Wiedemann syndrome, in Wilms' tumor, 549-550, 553

Bernard-Soulier syndrome, 2521, 283t, 284t, 285, 329t Biological tumor markers, 803-804 Birbeck granules, 604

Bladder, late effects of childhood cancer, 768, 769 Blalock-Taussig shunts, 335

antithrombotic therapy, 361 Bleeding time children and adults, 793t evaluation of platelets and platelet function, 292 newborns and children, 7931 Bleomycin, late effects of childhood cancer,

757-758, 768, 769 Blister cells, abnormalities in anemia, 7t Blood component therapy indications for small-volume RBC transfusion in preterm infants, 27, 28t intrauterine intravascular transfusion (IUIVT), 23 in iron-deficiency anemia packed red cell transfusion, 45 partial exchange transfusion, 45-46 maternofetal transfusion, polycythemia due to, 200-201

oncologic emergencies, 717-722

alloimmunization and refractoriness, 718

Blood component therapy (Continued)

benefits of leukoreduced blood products, 718t general guidelines, 719 graft versus host disease, 719 granulocyte transfusions, 721-722 platelet transfusions, 720-721, 721t red cell transfusions, 719-720 risk estimates of viral transmission, 7191 risks of transfusion complications per unit, 717t transfusion reactions, 717-718 transmission of infectious agents, 718-719 thrombocytopenia associated with erythroblastosis fetalis or exchange transfusion, 274 twin-to-twin transfusion, and prenatal blood loss, 15 Blood loss. See Hemorrhage Blood smear diagnosis of anemia, 1, 4/

evaluation of platelets and platelet function, 292 in iron deficiency anemia, 38 Blood volumes, estimated, 783t Bone disease, in Hodgkin disease, 462 Bone marrow disorders with neonatal thrombocytopenia, 280 with neutropenia, 223 erythroid series, 10/ examination, 1, 9t failure, 94-135 of all cell lines, 3t causes of, 95t infiltration, 3t inherited syndromes, 96t of single cell line, 2t foam cells in, 91

infiltration, 86-93, 86t, 87/, 88t, 89t, 90t involvement in Hodgkin disease, 463 megaloblastic, 10/ normoblastic, 10/ sideroblastic, 10/

transplantation (See Hematopoietic stem cell transplantation (HSCT)) Bone marrow aspiration, central nervous system malignancies, 517 Bone marrow cells, reference values, 796-797t Bone marrow transplantation See Hematopoietic stem cell transplantation Bone tumors, malignant, 585-602. See also Central nervous system (CNS) malignancies incidence, 585

age-specific incidence rate, 586/ secondary, late effects of childhood cancer, 771, 772t, 773 Bones, in SCD, 165-166

Bordetella pertussis, hematologic manifestations, 83

Brain stem tumors, 524-525

Brain tumors. See Central nervous system (CNS)

malignancies Budd-Chiari syndrome, 132, 341 Burkitt lymphoma. See Lymphoma, non-Hodgkin

(NHL) Burr cells, 6t

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