Cancer is also predicted by increased proportions of the central fat stores. This was first reported in a small number of endometrial carcinomas (57), and has subsequently been reported also for breast carcinoma (58) and confirmed in a larger study of endometrial carcinomas (59). Since these reports seem to suggest that the carcinomas predicted are localized to tissues which are sensitive to sex steroid hormones, one might speculate that the abnormalities of steroid hormone secretion found in abdominal obesity are also involved in this problem. Elevated androgens are closely associated with centralization of fat in women (21,60) as discussed in a preceding section, and probably originate from the adrenals as a consequence of a central drive of the HPA axis. Such abnormalities indicate disturbed secretions of sex steroid hormones which in an unknown way might be associated with these endocrine dependent carcinomas.
Was this article helpful?
Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.