Types of Smooth Muscle

The great diversity of the factors that can influence the contractile activity of smooth muscles from various organs has made it difficult to classify smooth-muscle fibers. Many smooth muscles can be placed, however, into one of two groups, based on the electrical characteristics of their plasma membrane: single-unit smooth muscles and multiunit smooth muscles.

Single-Unit Smooth Muscle The muscle fibers in a single-unit smooth muscle undergo synchronous activity, both electrical and mechanical; that is, the whole muscle responds to stimulation as a single unit. This occurs because each muscle fiber is linked to adjacent fibers by gap junctions, through which action potentials occurring in one cell are propagated to other cells by local currents. Therefore, electrical activity occurring anywhere within a group of single-unit smooth-muscle fibers can be conducted to all the other connected cells (Figure 11-40).

Some of the fibers in a single-unit muscle are pacemaker cells that spontaneously generate action potentials, which are conducted by way of gap junctions into fibers that do not spontaneously generate action potentials. The majority of cells in these muscles are not pacemaker cells.

Postganglionic sympathetic neuron

The contractile activity of single-unit smooth muscles can be altered by nerves, hormones, and local factors, using the variety of mechanisms described previously for smooth muscles in general. The extent to which these muscles are innervated varies considerably in different organs. The nerve terminals are often restricted to the regions of the muscle that contain pacemaker cells. By regulating the frequency of the pacemaker cells' action potentials, the activity of the entire muscle can be controlled.

One additional characteristic of single-unit smooth muscles is that a contractile response can often be induced by stretching the muscle. In several hollow or-gans—the uterus, for example—stretching the smooth muscles in the walls of the organ as a result of increases in the volume of material in the lumen initiates a contractile response.

The smooth muscles of the intestinal tract, uterus, and small-diameter blood vessels are examples of single-unit smooth muscles.

Multiunit Smooth Muscle Multiunit smooth muscles have no or few gap junctions, each fiber responds independently of its neighbors, and the muscle behaves as multiple units. Multiunit smooth muscles are richly innervated by branches of the autonomic nervous system. The contractile response of the whole muscle depends on the number of muscle fibers that are activated and on the frequency of nerve stimulation. Although stimulation of the nerve fibers to the muscle leads to some degree of depolarization and a contractile response, action potentials do not occur in most multiunit smooth muscles. Circulating hormones can increase or decrease contractile activity in multi-unit smooth muscle, but stretching does not induce contraction in this type of muscle. The smooth muscle in the large airways to the lungs, in large arteries, and attached to the hairs in the skin are examples of multi-unit smooth muscles.

Postganglionic parasympathetic neuron

Postganglionic sympathetic neuron

Postganglionic parasympathetic neuron

The Muscle Function Steps

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  • semhar
    Which is not characteristic of singleunit smooth muscle?
    8 years ago
  • logan mcintyre
    What purpose do smooth muscle fibres have in the lungs?
    8 years ago
  • ghenet futsum
    What are smooth muscles connected to?
    8 years ago
  • amiee
    Is intestinal smooth muscle multiunit?
    8 years ago
  • susanne
    What are some examples of smooth muscles?
    8 years ago
  • adiam
    What smooth muscle functions independently of its neighbors?
    7 years ago

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