Psychoactive Substances Dependence and Tolerance

In the previous sections, we mentioned several drugs used to combat altered states of consciousness. Psy-choactive drugs are also used as "recreational" or "street" drugs—the preferred term is now "substance" —in a deliberate attempt to elevate mood (eu-phorigens) and produce unusual states of consciousness ranging from meditational states to hallucinations. Virtually all the psychoactive substances exert their actions either directly or indirectly by altering neurotransmitter-receptor interactions in the biogenic amine—particularly dopamine—path-ways. For example, the primary effect of cocaine comes from its ability to block the reuptake of dopamine into the presynaptic axon terminal. As mentioned in Chapter 8, psychoactive substances are often chemically similar to neurotransmitters such as

PART TWO Biological Control Systems

Vander et al.: Human Physiology: The Mechanism of Body Function, Eighth Edition

PART TWO Biological Control Systems

Was this article helpful?

0 0
Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

Get My Free Ebook


Post a comment