Protein X is able to bind all three ligands, which have similar chemical structures. Protein Y, because of the shape of its binding site, can bind only ligand c. Protein Y, therefore, has a greater chemical specificity than protein X.

Although some binding sites have a chemical specificity that allows them to bind only one type of ligand, others are less specific and thus are able to bind a number of related ligands. For example, three different ligands can combine with the binding site of protein X in Figure 4-3 since a portion of each ligand is complementary to the shape of the binding site. In contrast, protein Y has a greater—that is, more limited— chemical specificity and can bind only one of the three ligands.

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Essentials of Human Physiology

Essentials of Human Physiology

This ebook provides an introductory explanation of the workings of the human body, with an effort to draw connections between the body systems and explain their interdependencies. A framework for the book is homeostasis and how the body maintains balance within each system. This is intended as a first introduction to physiology for a college-level course.

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