Figure 421

Formation of acetyl coenzyme A from pyruvic acid with the formation of a molecule of carbon dioxide.

Vander et al.: Human Physiology: The Mechanism of Body Function, Eighth Edition

PART ONE Basic Cell Functions

CoA SH

Oxaloacetate

COO-I

! 1 ! 1 ch2 I

^HO-C-COO-

ch2 j ^

Citrate

Malate

Oxaloacetate

Malate

Ketoglutarate

Isocitrate a-Ketoglutarate

Fumarate

Isocitrate

Fumarate a-Ketoglutarate

COO Succinate

S CoA

Succinyl coenzyme A

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