Figure

Complementary shapes of ligand and protein binding site determine the chemical specificity of binding.

Vander et al.: Human Physiology: The Mechanism of Body Function, Eighth Edition

I. Basic Cell Functions

4. Protein Activity and Cellular Metabolism

© The McGraw-Hill Companies, 2001

Protein Activity and Cellular Metabolism CHAPTER FOUR

Protein Activity and Cellular Metabolism CHAPTER FOUR

QO—OOCCCCCCCC

FIGURE 4-2

Amino acids that interact with the ligand at a binding site need not be at adjacent sites along the polypeptide chain, as indicated in this model showing the three-dimensional folding of a protein. The unfolded polypeptide chain is shown below.

FIGURE 4-2

Amino acids that interact with the ligand at a binding site need not be at adjacent sites along the polypeptide chain, as indicated in this model showing the three-dimensional folding of a protein. The unfolded polypeptide chain is shown below.

Protein X

Ligands fei II

Protein Y

Iff c il

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