Cm

Chemo Secrets From a Breast Cancer Survivor

Breast Cancer Survivors

Get Instant Access

76%

TUR-44 Partial-6

36%

48% (5 year)

C = cisplatin M = methotrexate A = adriamycin V = vinblastine

TUR = transurethral resection Partial = partial cystectomy CR = complete response

C = cisplatin M = methotrexate A = adriamycin V = vinblastine

TUR = transurethral resection Partial = partial cystectomy CR = complete response

54% of patients survived with an intact and functional bladder. These data serve as compelling evidence for the implementation of more conservative surgery (radical TUR or partial cystectomy) in combination with a multimodal approach, in an attempt to preserve a functioning bladder in spite of the presence of muscle-invasive disease. As a consequence, other investigators have reported on series employing conservative surgery with chemotherapy, the results of which are demonstrated in Table 1. Looking at all of these studies to determine the efficacy of a bladder sparing approach that incorporates surgery and chemotherapy, it becomes obvious that the Herr series stands alone with regard to results for survival and the retainment of a functional bladder.

As noted above, Dr Herr's report represents a group of highly selected patients where the M-VAC chemotherapy served as a litmus test to stratify patients for suitability for an organ-sparing approach. The other series in the table do not demonstrate this same rigorous selection bias and therefore the results are not as successful. One could predict that a patient with muscle-invasive bladder cancer being considered for bladder sparing with conservative surgery and chemotherapy would have a 50% chance of surviving five years from diagnosis and a 20-30% chance of keeping their bladder in situ.

Was this article helpful?

0 0
10 Ways To Fight Off Cancer

10 Ways To Fight Off Cancer

Learning About 10 Ways Fight Off Cancer Can Have Amazing Benefits For Your Life The Best Tips On How To Keep This Killer At Bay Discovering that you or a loved one has cancer can be utterly terrifying. All the same, once you comprehend the causes of cancer and learn how to reverse those causes, you or your loved one may have more than a fighting chance of beating out cancer.

Get My Free Ebook


Post a comment