Anticoagulation In Patients With Af

Firm data now exist for the use of anticoagulation in patients with AF. It is a well-established fact that AF leads to thrombus formation in the heart. Initially, it was believed that thrombus formation in the atria took several days to develop. More recent studies utilizing transesophageal echocardiography have demonstrated that in the absence of anticoagulation, the incidence of left atrial appendage thrombus formation

From: Contemporary Cardiology: Management of Cardiac Arrhythmias Edited by: L. I. Ganz © Humana Press Inc., Totowa, NJ

within 72 h of the onset of AF is 14%. One-half of the thrombi were mobile. Among patients with a recent thromboembolic event, the prevalence of left atrial thrombus did not differ between the group of patients with new-onset AF and those patients with AF of greater than 3 d duration. There was no significant difference between the incidence of left atrial thrombus formation in patients with AF of less than 2 d duration and those in individuals whose arrhythmia was present for 2-3 d (1).

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