Summary

To the novice, these models may appear as a bunch of numbers and equations pulled magically out of a hat. To summarize and help give some perspective on the structure of these models, in Table 4.6 is presented an overview of the currents and gating variables used in each of the four models presented above.

Table 4.6 Summary of currents for different ionic models.

Noble

Purkinje Fiber

Current

Ion

Gating Variables

INa

Na+

m, h

IKl

K+

Ik2

K+

n

lAn

Cl-

MNT

Purkinje fiber

Current

Ion

Gating Variables

INa

Na+

m, h

Isi

Ca2+

d, f

IKl

K+

IK2

K+

s

lxi

K+

X1

1X2

K+

X2

lei

Cl-

q, r

Wb

Na+

lei,b

Cl-

YNI

SA Nodal cells

Current

Ion

Gating Variables

INa

Na+

m, h

Is

d, f

Ik Ii

K+ leak

P

lh

q

BR

myocardial cells

Current

Ion

Gating Variables

INa

Na+

m, h, j

Is

Ca2+

d, f

Ik

K+

lx

K+

x

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